Developmental origins of renal disease: a translational approach
نویسندگان
چکیده
منابع مشابه
Developmental Origins of Chronic Renal Disease: An Integrative Hypothesis
Cardiovascular diseases are one of the leading causes of mortality. Hypertension (HT) is one of the principal risk factors associated with death. Chronic kidney disease (CKD), which is probably underestimated, increases the risk and the severity of adverse cardiovascular events. It is now recognized that low birth weight is a risk factor for these diseases, and this relationship is amplified by...
متن کاملDevelopmental origins of adult disease.
Variation in the quality or quantity of nutrients consumed during pregnancy can exert permanent and powerful effects upon the developing fetus. This programming of fetal development is emerging as a new risk factor for non-communicable diseases of adulthood, including coronary heart disease and the metabolic syndrome. Epidemiological studies show that indicators of nutritional deficit in pregna...
متن کاملDevelopmental Origins of Cardiovascular Disease
ardiovascular risk factors are identifiable in childhood and are predictive of adulthood risk for coronary artery disease.1 Autopsy studies of youths have established a strong association between cardiovascular risk factors and early stages of coronary atherosclerosis.2 Longitudinal observation studies have shown that coronary heart disease (CHD) risk factors measured in adolescence predict mar...
متن کاملDevelopmental origins of adult health and disease.
BRAIN SPARING A human baby receiving an inadequate supply of nutrients or oxygen may protect its brain. One way in which it does this is by diverting more blood to the brain at the expense of the blood supply to the trunk. The growth of organs such as the liver is therefore ‘‘traded off’’ to protect growth of the brain. Brain sparing may also be effected through metabolic processes such as insu...
متن کاملDevelopmental Origins of Health and Disease
1 School of Biosciences, University of Nottingham, Sutton Bonington, Loughborough LE12 5RD, UK 2University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USA 3Rowett Institute of Nutrition and Health, University of Aberdeen, Greenburn Road, Bucksburn, Aberdeen AB24 3FX, UK 4Faculty of Health Sciences, McMaster University, 1280 Main Street West, Hamilton, ON, Canada L...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2013
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.27.1_supplement.910.1